She earned her second Academy Award and BAFTA Award nominations for Best Leading Actress, winning her second Golden Globe Award for Best Actress – Motion Picture Musical or Comedy and the Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Leading Role.
Following the success of Chicago, she starred with Ewan Mc Gregor in the highly stylized romantic comedy Down with Love (2003), in which she played a woman who advocates female independence in the patriarchal and male chauvinist society of the 1950s and early 1960s.
She later gained widespread attention for her roles in the dramedy sports film Jerry Maguire (1996) and the comedy Nurse Betty (2000), for which she won her first Golden Globe Award for Best Actress in a Musical or Comedy.
She subsequently starred in the romantic comedy Bridget Jones's Diary (2001), obtaining nominations for the Academy Award and BAFTA Award for Best Leading Actress.
The film marked the actress' big break on screen as it received widespread critical acclaim and grossed over US3 million worldwide.
Roger Ebert, showing approval of Zellweger and Cruise's chemistry in the picture, wrote: "The film is often a delight, especially when Cruise and Zellweger are together on the screen.
She was also named Hasty Pudding's Woman of the Year in 2009, Zellweger's first major film role came in the horror sequel Texas Chainsaw Massacre: The Next Generation (1994), which she followed with a critically acclaimed appearance in Empire Records (1995).
One True Thing took in a modest US million in the US, Variety magazine's Todd Mc Carthy stated about Zellweger: "Projecting gravity and impatience that she hasn't shown before, Zellweger is outstanding as the smart young woman who resents the interruption to her life’s momentum but ends up growing in ways she never would have expected." For her work in both A Price Above Rubies and One True Thing, she tied with Central Station's Fernanda Montenegro as runners-up for the Best Actress prize at the 64th New York Film Critics Circle Awards, It revolves around a Rhode Island state trooper with split-personality disorder named Charlie, played by Carrey, who is assigned to escort Irene from Rhode Island to Massena, New York, to face what she believes is a false hit-and-run accusation set up by her mob-connected ex-boyfriend.
The film, released in 2000, was a commercial success, in which she played a Kansas waitress who suffers a nervous breakdown after witnessing her husband's murder, and starts obsessively pursuing her favorite soap actor.
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